2023年发表的论文

[25]  Yujia Zhao, Jianlin Yuan, Dai Xiao, Luwen Zhang, Cheng Li, Jingfei Hu, Rui Chen, Daili Song, Yiping Wen, Rui Wu, Qin Zhao, Senyan Du, Qigui Yan, Xinfeng Han, Xintian Wen, Sanjie Cao, Xiaobo Huang*. HSP90AB1 is a host factor that promotes porcine deltacoronavirus replication[J]. Journal of Biological Chemistry, 2024, 300(1): 105536. doi.org/10.1016/j.jbc.2023.105536.

[24] Shiqian Li, Dai Xiao, Luwen Zhang, Rui Chen, Daili Song, Yiping Wen, Rui Wu, Qin Zhao, Senyan Du, Qigui Yan, Sanjie Cao, Xiaobo Huang*. Porcine deltacoronavirus enters ST cells by clathrin-mediated endocytosis and does not require Rab5, Rab7, or Rab11[J]. Microbiology Spectrum. 2023, 11(6): doi.org/10.1128/spectrum.02553-23.

[23] Daili Song, Yujia Zhao, Ying Sun, Yixiao Liang, Rui Chen, Yiping Wen, RuiWu, Qin Zhao, Senyan Du, Qigui Yan, Xinfeng Han, Sanjie Cao, Xiaobo Huang*. HSP90AB1 is a host factor required for transmissible gastroenteritis virus infection[J]. Internationl Journal of Molecular Science. 2023, 24(21): 15971. doi.org/10.3390/ijms242115971.

[22] Yimin Wen, Rui Chen, Junpeng Yang, Enbo Yu, Weizhe Liu, Yijie Liao, Yiping Wen, Rui Wu, Qin Zhao, Senyan Du, Qigui Yan, Xinfeng Han, Sanjie Cao, Xiaobo Huang*. Identification of potential SLA-I-specific T-cell epitopes within the structural proteins of porcine deltacoronavirus[J], International Journal of Biological Macromolecules. 2023, 251: 126327. doi.org/10.1016/j.ijbiomac.2023.126327.

[21]  Dai Xiao, Luwen Zhang, Shiqian Li, Yixiao Liang, Rui Wu, Yiping Wen, Qigui Yan,Senyan Du, Qin Zhao, Xinfeng Han, Jianling Song, Sanjie Cao, Xiaobo Huang*. Characterization, phylogenetic analysis, and pathogenicity of a novel genotype 2 porcine Enterovirus G[J]. Virus Research, 2023, 335: 199185. doi.org/10.1016/j.virusres.

[20] Rui Chen, Yimin Wen, Enbo Yu, Junpeng Yang, Yixiao Liang, Daili Song, Yiping Wen, Rui Wu, Qin Zhao, Senyan Du, Qigui Yan, Xinfeng Han, Sanjie Cao, Xiaobo Huang*. Identification of an immunodominant neutralizing epitope of porcine deltacoronavirus spike protein[J]. International Journal of Biological Macromolecules, 2023, 242(4): 125190. doi.org/10.1016/j.ijbiomac.2023.125190.

[19] Qi Wang, Shuqing Yang, Ke Yang, Xinran Li, Yu Dai, Yi Zheng, Sanjie Cao, Qigui Yan, Xiaobo Huang, Yiping Wen, Qin Zhao, Senyan Du, Yifei Lang, Shan Zhao, Rui Wu*. CD4 is an important Host Factor for Japanese Encephalitis Virus Entry and Replication in PK-15 Cells. Veterinary Microbiology, 2023, 287,109913.

[18] Weimin Xu, Ke Yang, Yi Zheng, Sanjie Cao, Qigui Yan, Xiaobo Huang, Yiping Wen, Qin Zhao, Senyan Du, Yifei Lang, Shan Zhao and Rui Wu*. BAK Mediated Pyroptosis Promotes Japanese Encephalitis Virus Proliferation in Porcine Kidney 15 Cells[J]. Viruses, 2023, 15, 974.

[17] Wei Liang, Hang Xiao, Jia-Yong Chen, Yung-Fu Chang, San-Jie Cao, Yi-Ping Wen, Rui Wu, Sen-Yan Du, Qi-Gui Yan, Xiao-Bo Huang, Qin Zhao*. Immunogenicity and protective efficacy of a multi-epitope recombinant toxin antigen of Pasteurella multocida against virulent challenge in mice[J]. Vaccine, 2023, 41:2387-2396, doi: 10.1016/j.vaccine.2023.02.070.

[16] Hang Xiao, Qin Zhao, Jianlin Yuan, Wei Liang, Rui Wu, Yiping Wen, Senyan Du, Yiping Wang, Shan Zhao, Yifei Lang, Qigui Yan, Xiaobo Huang, Sanjie Cao*. IFN-γ promotes PANoptosis in Pasteurella multocida toxin-induced pneumonia in mice [J]. Veterinary Microbiology, 2023, 285: 109848, doi:10.1016/j.vetmic.2023.109848.

[15] Geyan Liu,Kang Wang,Zhen Yang,Xiaoyu Tang,Yungfu Chang,Dai Ke,Xinwei Tang,Bangdi Hu,Yiwen Zhang,Sanjie Cao,Xiaobo Huang,Qigui Yan,Rui Wu,Qin Zhao,Senyan Du,Xintian Wen and Yiping Wen*. Identification of a Novel Linear B-Cell Epitope of HbpA Protein from Glaesserella parasuis Using Monoclonal Antibody [J]. International Journal of Molecular Sciences, 2023, 24,8638:1-16.    

[14] Zhen Yang,Yiwen Zhang,Senyan Du,Qin Zhao,Xiaobo Huang,Rui Wu,Qigui Yan,Xinfeng Han,Sanjie Cao,Yung-Fu Chang,Yiping Wen*. Upregulation of occludin by cytolethal distending toxin facilitates Glaesserella parasuis adhesion to respiratory tract cells[J]. INFECTION AND IMMUNITY, 2023, 91, 12, 10.1128/iai.00351-23.

[13] Zhao S, Hu H, Lan J, Yang Z, Peng Q, Yan L, Luo L, Wu L, Lang Y, Yan Q*. Characterization of a fatal feline panleukopenia virus derived from giant panda with broad cell tropism and zoonotic potential. Front Immunol. 2023 Aug 17;14:1237630.

[12] Zhao S, Han X, Lang Y, Xie Y, Yang Z, Zhao Q, Wen Y, Xia J, Wu R, Huang X, Huang Y, Cao S, Lan J, Luo L, Yan Q*. Development and efficacy evaluation of remodeled canine parvovirus-like particles displaying major antigenic epitopes of a giant panda derived canine distemper virus. Front Microbiol. 2023 Feb 27;14:1117135.

[11] Qianling Peng,Jiqiang Shi,Yifei Lang,Yulan Zhu,Xiaobo Huang,Sanjie Cao,Qigui Yan*,Shan Zhao*. Phylogenetic Analysis and Serological Investigation of Porcine Circovirus Indicates Frequent Infection with Various Subtypes[J]. Int. J. Mol. Sci. 2023, 24(21), 15850.doi:10.3390/ijms242115850

[10] Qianling Peng,Zhisong Yang,Lin Wu,Peilun Yu,Qiang Li,Jingchao Lan,Li Luo,Shan Zhao,Qigui Yan*. Evaluation of the Inactivation Efficacy of Four Disinfectants for Feline Parvovirus Derived from Giant Panda[J]. Microorganisms, 2023, 11(7), 1844.doi: 10.3390/microorganisms11071844

[9] Pei-Lun Yu,Rui Wu,San-Jie Cao,Yi-Ping Wen,Xiao-Bo Huang,Shan Zhao,Yi-Fei Lang,Qin Zhao,Ju-Chun Lin,Sen-Yan Du,Shu-Min Yu,Qi-Gui Yan*.Pseudorabies virus exploits N6-methyladenosine modification to promote viral replication [J]. Frontiers in Microbiology, 2023, 14.doi: 10.3389/fmicb.2023.1087484

[8] Huan-Huan Shen,Qin Zhao,Yi-Ping Wen,Rui Wu,Sen-Yan Du,Xiao-Bo Huang,Xin-Tian Wen,San-Jie Cao,Lei Zeng,Qi-Gui Yan*.Porcine reproductive and respiratory syndrome virus upregulates SMPDL3B to promote viral replication by modulating lipid metabolism [J]. IScience, 2023, 26(8): 107450.doi: 10.1016/j.isci.2023.107450

[7] 徐炜民,邓鑫,伍锐*. 促凋亡蛋白BAK的功能及在病毒感染中作用的研究进展[J]. 中国生物工程杂志, 2023, 43(2/3):130-140.

[6] 徐昌豪,朱茜,和易,刘雨薇,黄裕恬,李睿冬,曹三杰,黄小波,颜其贵,伍锐,文翼平,郎一飞,赵勤,赵珊,王一平,胡雅劼,杜森焱*. 致倦库蚊成蚊吸食血餐和感染乙型脑炎病毒前后中肠细菌多样性分析[J]. 昆虫学报, 2023, 66(8): 1031-1041.

[5] 李金峰,袁建林,赵勤,杜森焱,伍锐,文翼平,黄小波,颜其贵,曹三杰*. 重组多杀性巴氏杆菌毒素的猪细胞毒性及其小鼠病理模型的建立[J]. 农业生物技术学报, 2023,31(1):213-222. DOI:10.3969/j.issn.1674-7968.2023.01.021.

[4] 王康,刘格言,王宇,杨振,唐欣巍,曹三杰,黄小波,颜其贵,伍锐,赵勤,杜森焱,文心田,文翼平*. 副猪革拉瑟菌影递送猪圆环病毒2型DNA二联疫苗的制备及小鼠免疫效果评价[J]. 畜牧兽医学报, 2023, 12(1):1-20.

[3] 孙珊珊,其美拉姆,李强,曾南方,郑诚,张白玉,颜其贵*. 表达PRRSV NADC30-like毒株GP5-M的重组伪狂犬病病毒的构建及其生物学特性探究[J].浙江农业学报, 2023, 35(11):2555-2567.

[2] 李强,严立恒,兰景超,邓英,孙珊珊,罗娌,史纪强,颜其贵*. 大熊猫源犬细小病毒VP2基因的原核表达及间接ELISA检测方法的建立[J].云南农业大学学报(自然科学), 2023, 38(05):795-802.

[1] 彭茜翎,王如意,乔美萍,周磊,王洪永,蒋本模,吴杰,杨杰,其美拉姆,颜其贵*. 一株林麝源弗格森埃希菌的分离鉴定及耐药性[J].野生动物学报, 2023, 44(04):870-877.


2022年发表的论文

[19] Tang XY, Yang Z, Dai K, Liu GY, Chang YF, Tang XW, Wang K, Zhang YW, Hu BD, Cao SJ, Huang XB, Yan QG, Wu R, Zhao Q, Du SY, Lang YF, Han XF, Huang Y, Wen XT, Wen YP. The molecular diversity of transcriptional factor TfoX is a determinant in natural transformation in Glaesserella parasuis. [J].Frontiers in Microbiology, 10.3389/fmicb.2022.948633

[18] Yang Z, Tang XW, Wang K, Dai K, Chang YF , Du SY, Zhao Q, Huang XB, Wu R,, Yan QG, Cao SJ, Wen YP. Metal Ion Periplasmic-Binding Protein YfeA of Glaesserella parasuis Induces the Secretion of Pro-Inflammatory Cytokines of Macrophages via MAPK and NF-κB Signaling through TLR2 and TLR4. [J]. International Journal of Molecular Sciences. 2022; 23:9627.

[17] Liang W, Quan K, Zhao Q, Wu Y, Mu Y, Cao S. Development of a double-antibody sandwich ELISA targeting the receptor binding domain of TcdB toxin of ST11 type Clostridium difficile of porcine origin. [J]. Sheng Wu Gong Cheng Xue Bao. 2022; 38(1):185-195.

[16] Zhao Y, Chen R, Xiao D, Zhang L, Song D, Wen Y, Wu R, Zhao Q, Du S, Wen X, Cao S, Huang X. A Comparative Transcriptomic Analysis Reveals That HSP90AB1 Is Involved in the Immune and Inflammatory Responses to Porcine Deltacoronavirus Infection. [J]. Int J Mol Sci. 2022; 23(6):3280.

[15] Yang Z, Tang X, Wang K, Dai K, Chang YF, Du S, Zhao Q, Huang X, Wu R, Yan Q, Cao S, Wen Y. Metal Ion Periplasmic-Binding Protein YfeA of Glaesserella parasuis Induces the Secretion of Pro-Inflammatory Cytokines of Macrophages via MAPK and NF-κB Signaling through TLR2 and TLR4. [J]. Int J Mol Sci. 2022; 23(17):9627.

[14] Tang X, Yang Z, Dai K, Liu G, Chang YF, Tang X, Wang K, Zhang Y, Hu B, Cao S, Huang X, Yan Q, Wu R, Zhao Q, Du S, Lang Y, Han X, Huang Y, Wen X, Wen Y. The molecular diversity of transcriptional factor TfoX is a determinant in natural transformation in Glaesserella parasuis. [J]. Front Microbiol. 2022; 13:948633.

[13] Zheng Y, Xu Y, Xu W, Cao S, Yan Q, Huang X, Wen Y, Zhao Q, Du S, Lang Y, Zhao S, Wu R. CD38 Enhances TLR9 Expression and Activates NLRP3 Inflammasome after Porcine Parvovirus Infection. [J]. Viruses. 2022; 14(6):1136.

[12] Xiang H, Wen X, Wen Y, Zhang H, Cao S, Huang X, Wu R, Zhao Q. Development and application of a visual microarray for synchronously detecting H5N1, H7N9 and H9N2 avian influenza virus RNA. [J]. J Virol Methods. 2022; 301:114371.

[11] Zhao Y, Xiao D, Zhang L, Song D, Chen R, Li S, Liao Y, Wen Y, Liu W, Yu E, Wen Y, Wu R, Zhao Q, Du S, Wen X, Cao S, Huang X. HSP90 inhibitors 17-AAG and VER-82576 inhibit porcine deltacoronavirus replication in vitro. [J]. Vet Microbiol. 2022; 265:109316.

[10] Li S, Xiao D, Zhao Y, Zhang L, Chen R, Liu W, Wen Y, Liao Y, Wen Y, Wu R, Han X, Zhao Q, Du S, Yan Q, Wen X, Cao S, Huang X. Porcine Deltacoronavirus (PDCoV) Entry into PK-15 Cells by Caveolae-Mediated Endocytosis. [J]. Viruses. 2022; 14(3):496.

[9] Qu H, Wen Y, Hu J, Xiao D, Li S, Zhang L, Liao Y, Chen R, Zhao Y, Wen Y, Wu R, Zhao Q, Du S, Yan Q, Wen X, Cao S, Huang X*. Study of the inhibitory effect of STAT1 on PDCoV infection[J]. Veterinary Microbiology, 2022 Mar; 266: 109333.

[8] 何绿琴,闫雪锋,文心田,曹三杰,黄小波,伍 锐,赵 勤,文翼平. 副猪嗜血杆菌qseB、qseC双基因缺失株的 构建及生物学特性[J]. 畜牧兽医学报, 2022, 53(2):529-537

[7] 梁伟,全柯吉,赵勤,武耀民,穆瑜,曹三杰. 猪源ST11型艰难梭菌TcdB毒素受体结合域双抗体夹心ELISA的建立[J].生物工程学报,2022,38(01):185-195.

[6] 瞿欢,胡靖飞,李施倩,肖黛,张路文,付嘉钰,赵玉佳,陈汭,文翼平,伍锐,赵勤,颜其贵,文心田,曹三杰,黄小波. 不同动物源性细胞系对猪丁型冠状病毒的易感性[J].微生物学报,2022,62(02):672-685.

[5] 宋代丽,杨富升,陈钰乔,孙凡媛,陈汭,曹三杰,黄小波. 猪δ冠状病毒M蛋白的截短表达及间接ELISA方法的建立[J].农业生物技术学报,2022,30(02):402-412.

[4] 何绿琴,闫雪锋,文心田,曹三杰,黄小波,伍锐,赵勤,文翼平. 副猪嗜血杆菌qseB、qseC双基因缺失株的构建及生物学特性[J].畜牧兽医学报,2022,53(02):529-537.

[3] 赵玉佳,陈汭,宋代丽,张路文,肖黛,李施倩,文翼平,伍锐,赵勤,杜森焱,颜其贵,文心田,曹三杰,黄小波. 人氨基肽酶N在猪丁型冠状病毒感染HEK293细胞中的作用[J].畜牧兽医学报,2022,53(05):1587-1597.

[2] 郑艺,徐伊璇,彭文婧,曹三杰,颜其贵,黄小波,文翼平,赵勤,杜森焱,伍锐. 猪细小病毒HNLY201301株遗传特性及其对小鼠的致病性研究[J].四川农业大学学报,2022,40(03):413-420.

[1] 肖黛,张路文,李施倩,俞恩波,曹三杰,黄小波.猪肠病毒G(EV-G)荧光定量PCR检测方法的建立与四川地区分子流行病学调查[J]. 微生物学通报,2022,49(11):4809-4820.


2021年发表的论文

[7] He L, Yan X, Dai K, Wen X, Cao S, Huang X, Wu R, Zhao Q, Huang Y, Yan Q, Ma X, Han X, Wen Y. Comparative transcriptome analysis reveals that deletion of CheY influences gene expressions of ABC transports and metabolism in Haemophilus parasuis. [J]. Funct Integr Genomics. 2021; 21(5-6):695-707.

[6] Dai K, Yang Z, Ma X, Chang YF, Cao S, Zhao Q, Huang X, Wu R, Huang Y, Xia J, Yan Q, Han X, Ma X, Wen X, Wen Y. Deletion of Polyamine Transport Protein PotD Exacerbates Virulence in Glaesserella (Haemophilus) parasuis in the Form of Non-biofilm-generated Bacteria in a Murine Acute Infection Model. [J]. Virulence. 2021; 12(1):520-546.

[5] Xu K, Zhao Q, Jiang HZ, Mou XR, Chang YF, Cao YQ, Miao C, Wu R, Wen YP, Huang XB, Yan QG, Du SY, Cao SJ. Molecular and functional characterization of HtrA protein in Actinobacillus pleuropneumoniae. [J]. Vet Microbiol. 2021; 257:109058.

[4] Yu PL, Cao SJ, Wu R, Zhao Q, Yan QG. Regulatory effect of m6 A modification on different viruses. [J]. J Med Virol. 2021; 93(11):6100-6115.

[3] 瞿欢,李成,陈汭,廖艺杰,曹三杰,文翼平,颜其贵,黄小波. 猪δ冠状病毒S1-CTD的截短表达及间接ELISA抗体方法的建立[J].生物技术通报,2021,37(05):273-280.

[2] 梁伟,王博,赵勤,全柯吉,武耀民,缪昌,曹三杰. 四川地区猪源艰难梭菌分子分型调查[J].微生物学通报,2021,48(10):3726-3735.

[1] 王佳凡,郑博文,杨超,马晓平,曹三杰,黄小波. 四川猪传染性胸膜肺炎放线杆菌耐药基因流行规律与表型相关性研究[J].云南农业大学学报(自然科学),2021,36(04):631-639.


2020年发表的论文

[6] Fu J, Chen R, Hu J, Qu H, Zhao Y, Cao S, Wen X, Wen Y, Wu R, Zhao Q, Ma X, Huang X. Identification of a Novel Linear B-Cell Epitope on the Nucleocapsid Protein of Porcine Deltacoronavirus. [J]. Int J Mol Sci. 2020; 21(2):648.

[5] Chen R, Fu J, Hu J, Li C, Zhao Y, Qu H, Wen X, Cao S, Wen Y, Wu R, Zhao Q, Yan Q, Huang Y, Ma X, Han X, Huang X. Identification of the immunodominant neutralizing regions in the spike glycoprotein of porcine deltacoronavirus. [J]. Virus Res. 2020; 276:197834.

[4] 郭广超, 周于用, 武耀民, 伍锐, 赵勤, 文心田, 黄小波, 文翼平, 曹三杰. 乙型脑炎病毒NS2A-C60A位点突变对其生物学特性影响研究[J]. 中国生物工程杂志, 2020, 40(9):1-10.

[3] 付嘉钰,陈汭,黄小波,曹三杰,文心田,文翼平,赵勤,伍锐. 1株猪δ冠状病毒N蛋白单克隆抗体制备与鉴定[J].微生物学通报,2020,47(06):1847-1856.

[2] 胡靖飞,滑翔,黄小波,赵玉佳,曹三杰,文心田,文翼平,伍锐,赵勤. 联合共检四种猪腹泻病毒的寡核苷酸芯片的构建及应用[J].农业生物技术学报,2020,28(02):349-359.

[1] 陈汭,付嘉钰,刘浩宇,李成,赵玉佳,胡靖飞,瞿欢,曹三杰,文心田,文翼平,赵勤,伍锐,黄小波.猪δ冠状病毒(PDCoV)N蛋白的原核表达及多克隆抗体制备[J].生物技术通报,2020,36(08):104-110.


2019年发表的论文

[9] Chai C, Palinski R, Xu Y, Wang Q, Cao S, Geng Y, Zhao Q, Wen Y, Huang X, Yan Q, Ma X, Wen X, Huang Y, Han X, Ma W, Wu R. Aerosol and Contact Transmission Following Intranasal Infection of Mice with Japanese Encephalitis Virus. [J]. Viruses. 2019; 11(1):87.

[8] Dai K, Ma X, Yang Z, Chang YF, Cao S, Zhao Q, Huang X, Wu R, Huang Y, Yan Q, Han X, Ma X, Wen X, Wen Y. Polyamine Transport Protein PotD Protects Mice against Haemophilus parasuis and Elevates the Secretion of Pro-Inflammatory Cytokines of Macrophage via JNK-MAPK and NF-κB Signal Pathways through TLR4. [J]. Vaccines (Basel). 2019; 7(4):216.

[7] Xu Y, Wang Q, Wei B, Huang X, Wen Y, Yan Q, Ma X, Zhao Q, Cao S, Huang Y, Wen X, Han X, Bai Y, Wu R. Enhanced Immune Responses Against Japanese Encephalitis Virus Infection Using Japanese Encephalitis Live-Attenuated Virus Adjuvanted with Montanide GEL 01 ST in Mice. [J]. Vector Borne Zoonotic Dis. 2019; 19(11):835-843.

[6] Dai K, Yang Z, Chang YF, He L, Cao S, Zhao Q, Huang X, Wu R, Huang Y, Yan Q, Han X, Ma X, Wen X, Wen Y. Construction of targeted and integrative promoter-reporter plasmids pDK-K and pDK-G to measure gene expression activity in Haemophilus parasuis. [J]. Microb Pathog. 2019; 134:103565.

[5] Cao YQ, Yuan L, Zhao Q, Yuan JL, Miao C, Chang YF, Wen XT, Wu R, Huang XB, Wen YP, Yan QG, Huang Y, Han XF, Ma XP, Cao SJ. Hsp40 Protein DNAJB6 Interacts with Viral NS3 and Inhibits the Replication of the Japanese Encephalitis Virus. [J]. Int J Mol Sci. 2019; 20(22):5719.

[4] Li Y, Cao S, Zhang L, Yuan J, Zhao Q, Wen Y, Wu R, Huang X, Yan Q, Huang Y, Ma X, Han X, Miao C, Wen X. A requirement of TolC1 for effective survival, colonization and pathogenicity of Actinobacillus pleuropneumoniae. [J]. Microb Pathog. 2019; 134:103596.

[3] Chen R, Fu J, Hu J, Li C, Zhao Y, Qu H, Wen X, Cao S, Wen Y, Wu R, Zhao Q, Yan Q, Huang Y, Ma X, Han X, Huang X. Identification of the immunodominant neutralizing regions in the spike glycoprotein of porcine deltacoronavirus. [J]. Virus Res. 2020; 276:197834.

[2] Zhao Y, Qu H, Hu J, Fu J, Chen R, Li C, Cao S, Wen Y, Wu R, Zhao Q, Yan Q, Wen X, Huang X. Characterization and Pathogenicity of the Porcine Deltacoronavirus Isolated in Southwest China. [J]. Viruses. 2019; 11(11):1074.

[1] 胡靖飞,尹人杰,黄小波,刘志鹏,赵玉佳,曹三杰,文心田,文翼平,赵勤,伍锐. 共检猪流行性腹泻病毒、猪传染性胃肠炎病毒和猪轮状病毒的cDNA芯片的技术优化[J].四川农业大学学报,2019,37(04):542-549+578.


2018年发表的论文

[20] Zhang F, Zhao Q, Tian J, Chang YF, Wen X, Huang X, Wu R, Wen Y, Yan Q, Huang Y, Ma X, Han X, Miao C, Cao S. Effective Pro-Inflammatory Induced Activity of GALT, a Conserved Antigen in A. Pleuropneumoniae, Improves the Cytokines Secretion of Macrophage via p38, ERK1/2 and JNK MAPKs Signal Pathway. [J]. Front Cell Infect Microbiol. 2018; 8:337.

[19] Zhang F, Zhao Q, Quan K, Zhu Z, Yang Y, Wen X, Chang YF, Huang X, Wu R, Wen Y, Yan Q, Huang Y, Ma X, Han X, Cao S. Galactose-1-phosphate uridyltransferase (GalT), an in vivo-induced antigen of Actinobacillus pleuropneumoniae serovar 5b strain L20, provided immunoprotection against serovar 1 strain MS71. [J]. PLoS One. 2018; 13(6): e0198207.

[18] Zhou Y, Wu R, Zhao Q, Chang YF, Wen X, Feng Y, Huang X, Wen Y, Yan Q, Huang Y, Ma X, Han X, Cao S. Mutation of I176R in the E coding region weakens Japanese encephalitis virus neurovirulence, but not its growth rate in BHK-21 cells. [J]. Arch Virol. 2018; 163(5):1351-1355.

[17] Dai K, Wen X, Chang YF, Cao S, Zhao Q, Huang X, Wu R, Huang Y, Yan Q, Han X, Ma X, Wen Y. A streptomycin resistance marker in H. parasuis based on site-directed mutations in rpsL gene to perform unmarked in-frame mutations and to verify natural transformation. [J]. PeerJ. 2018; 6: e4253.

[16] Xu K, Zhao Q, Wen X, Wu R, Wen Y, Huang X, Huang Y, Yan Q, Han X, Ma X, Chang YF, Cao S. A trivalent Apx-fusion protein delivered by E. coli outer membrane vesicles induce protection against Actinobacillus pleuropneumoniae of serotype 1 and 7 challenge in a murine model. [J]. PLoS One. 2018; 13(1): e0191286.

[15] Zhou Y, Wu R, Feng Y, Zhao Q, Wen X, Huang X, Wen Y, Yan Q, Huang Y, Ma X, Han X, Cao S. Genomic changes in an attenuated genotype I Japanese encephalitis virus and comparison with virulent parental strain. [J]. Virus Genes. 2018; 54(3):424-431.

[14] Dai K, He L, Chang YF, Cao S, Zhao Q, Huang X, Wu R, Huang Y, Yan Q, Han X, Ma X, Wen X, Wen Y. Basic Characterization of Natural Transformation in a Highly Transformable Haemophilus parasuis Strain SC1401. [J]. Front Cell Infect Microbiol. 2018; 8:32.

[13] Wen Y, Wen Y, Wen X, Cao S, Huang X, Wu R, Zhao Q, Liu M, Huang Y, Yan Q, Han X, Ma X, Dai K, Ding L, Liu S, Yang J. OxyR of Haemophilus parasuis is a global transcriptional regulator important in oxidative stress resistance and growth. [J]. Gene. 2018; 643:107-116.

[12] He L, Dai K, Wen X, Ding L, Cao S, Huang X, Wu R, Zhao Q, Huang Y, Yan Q, Ma X, Han X, Wen Y. QseC Mediates Osmotic Stress Resistance and Biofilm Formation in Haemophilus parasuis. [J]. Front Microbiol. 2018; 9:212.

[11] Chai C, Wang Q, Cao S, Zhao Q, Wen Y, Huang X, Wen X, Yan Q, Ma X, Wu R. Serological and molecular epidemiology of Japanese encephalitis virus infections in swine herds in China, 2006-2012. [J]. J Vet Sci. 2018; 19(1):151-155.

[10] 刘扶摇,王梦君,李雨轩,夏千惠,王侨,曹三杰,伍锐. Montanide~(TM) Gel 01 ST水性佐剂对猪乙型脑炎活疫苗免疫小鼠后的早期免疫保护效果的影响[J].中国预防兽医学报,2018,40(01):40-44

[9] 田绍超,王侨,李琦,李志强,曹三杰,伍锐. 猪胸膜肺炎放线杆菌血清5型的致病性及感染小鼠后的组织分布研究[J].中国预防兽医学报,2018,40(02):156-159.

[8] 魏海林,付丹,王正皓,文心田,曹三杰,黄小波,伍锐,赵勤,文翼平. 四川省副猪嗜血杆菌分离株β-内酰胺类药物药敏特性及质粒介导耐药基因检测研究[J].中国预防兽医学报,2018,40(03):186-189.

[7] 王侨,柴春霞,冯瑶,曹钰莹,邓李霜,曹三杰,黄小波,文翼平,赵勤,伍锐. 猪乙型脑炎病毒基因Ⅰ型弱毒株免疫小鼠后诱导INF-γ的能力[J].四川农业大学学报,2018,36(02):233-237.

[6] 李成,张雨迪,黄小波,刘浩宇,刘志鹏,赵玉佳,曹三杰,文心田,文翼平,赵勤,伍锐. 猪丁型冠状病毒S1基因的克隆、原核表达及多克隆抗体制备[J].畜牧兽医学报,2018,49(06):1256-1264.

[5] 柴春霞,王侨,赖雅兰,徐伊璇,文心田,曹三杰,黄小波,文翼平,赵勤,伍锐. 猪乙型脑炎病毒SCYA201201株感染小鼠后突破血脑屏障能力研究[J].浙江农业学报,2018,30(06):926-931.

[4] 朱璐,范小兵,王正皓,代科,文心田,曹三杰,赵勤,文翼平. 血清5型和13型副猪嗜血杆菌二价灭活苗的制备和免疫效果评价[J].四川农业大学学报,2018,36(04):514-519.

[3] 刘浩宇,黄小波,李成,刘志鹏,吴盈盈,赵玉佳,曹三杰,文心田,文翼平,伍锐,赵勤,刘凤华. 猪德尔塔冠状病毒(PDCoV)RT-PCR检测方法的建立与应用[J].农业生物技术学报,2018,26(09):1631-1638.

[2] 杨振,谨瑾,马小雨,代科,王正皓,曹三杰,黄小波,伍锐,赵勤,文翼平. 副猪嗜血杆菌高自然转化效率菌株的筛选及全基因组测序[J].畜牧兽医学报,2018,49(11):2442-2450.

[1] 王婉蓉,代科,马小雨,杨振,曹三杰,黄小波,赵勤,伍锐,文翼平. 副猪嗜血杆菌链霉素耐药基因rpsL、rrs分析和关键位点的鉴定[J].中国预防兽医学报,2018,40(11):1061-1065.


2017年发表的论文

[10] Zhu Z, Zhao Q, Zhao Y, Zhang F, Wen X, Huang X, Wen Y, Wu R, Yan Q, Huang Y, Ma X, Han X, Cao S. Polyamine-binding protein PotD2 is required for stress tolerance and virulence in Actinobacillus pleuropneumoniae. [J]. Antonie Van Leeuwenhoek. 2017; 110(12):1647-1657.

[9] Li Y, Cao S, Zhang L, Yuan J, Yang Y, Zhu Z, Wen Y, Wu R, Zhao Q, Huang X, Yan Q, Huang Y, Ma X, Wen X. TolC2 is required for the resistance, colonization and virulence of Actinobacillus pleuropneumoniae. [J]. J Med Microbiol. 2017; 66(8):1170-1176.

[8] Wang Z, Zhao Q, Wei H, Wen X, Cao S, Huang X, Wu R, Yan Q, Huang Y, Wen Y. Prevalence and seroepidemiology of Haemophilus parasuis in Sichuan province, China. [J]. PeerJ. 2017; 5

[7] Liu H, Wu R, Yuan L, Tian G, Huang X, Wen Y, Ma X, Huang Y, Yan Q, Zhao Q, Cao S, Wen X. Introducing a cleavable signal peptide enhances the packaging efficiency of lentiviral vectors pseudotyped with Japanese encephalitis virus envelope proteins. [J]. Virus Res. 2017; 229:9-16.

[6] Zhao Qin, Yang Zhao-Si, Cao San-Jie, Chang Yung-Fu, Cao Yu-Qin, Li Jia-Bing, Yao Zi-Xuan, Wen Yi-Ping, Huang Xiao-Bo, Wu Rui, Yan Qi-Gui, Huang Yong, Ma Xiao-Ping, Han Xin-Feng, Wu Yinglong. Acute oral toxicity test and assessment of combined toxicity of cadmium and aflatoxin B in kunming mice.[J] .Food Chem. Toxicol., 2019, 131: 110577.

[5] 李莹馨,原茜,王震宇,黄磊,覃文君,赵勤. 魔芋葡甘露聚糖对镉所致的LO2细胞毒性损伤的影响, 西南农业学报, 2019,32(8): 1918-1923.

[4] 徐魁,王巍,文心田,黄小波,伍锐,文翼平,赵勤,曹三杰. 四川主要养猪地区猪2型链球菌血清流行病学调查[J].中国预防兽医学报,2017,39(05):370-373.

[3] 冯瑶,岳辉喜,刘洪明,曹三杰,伍锐,黄小波,文翼平,赵勤,文心田. 基因Ⅰ型猪乙型脑炎灭活疫苗免疫原性评价[J].畜牧兽医学报,2017,48(05):889-895.

[2] 代科,谨瑾,文心田,张禄滑,李英,曹三杰,黄小波,伍锐,赵勤,文翼平. 副猪嗜血杆菌聚胺转运蛋白PotD重组亚单位疫苗的制备及其免疫保护效力的评价[J].中国兽医科学,2017,47(08):981-987.

[1] 谨瑾,代科,文心田,何绿琴,张禄滑,赵玉佳,曹三杰,黄小波,伍锐,赵勤,文翼平. 副猪嗜血杆菌自然转化方法的建立及条件优化[J].农业生物技术学报,2017,25(12):2058-2065.


2016年发表的论文

[23] Li Y, Cao S, Zhang L, Yuan J, Lau GW, Wen Y, Wu R, Zhao Q, Huang X, Yan Q, Huang Y, Wen X. Absence of TolC Impairs Biofilm Formation in Actinobacillus pleuropneumoniae by Reducing Initial Attachment. [J]. PLoS One. 2016; 11(9): e0163364.

[22] Zhang F, Cao S, Zhu Z, Yang Y, Wen X, Chang YF, Huang X, Wu R, Wen Y, Yan Q, Huang Y, Ma X, Zhao Q. Immunoprotective Efficacy of Six In vivo-Induced Antigens against Actinobacillus pleuropneumoniae as Potential Vaccine Candidates in Murine Model. [J]. Front Microbiol. 2016; 7:1623.

[21] Li Y, Cao S, Zhang L, Lau GW, Wen Y, Wu R, Zhao Q, Huang X, Yan Q, Huang Y, Wen X. A TolC-Like Protein of Actinobacillus pleuropneumoniae Is Involved in Antibiotic Resistance and Biofilm Formation. [J]. Front Microbiol. 2016; 7:1618.

[20] Liu H, Wu R, Liu K, Yuan L, Huang X, Wen Y, Ma X, Yan Q, Zhao Q, Wen X, Cao S. Enhanced immune responses against Japanese encephalitis virus using recombinant adenoviruses coexpressing Japanese encephalitis virus envelope and porcine interleukin-6 proteins in mice. [J]. Virus Res. 2016; 222:34-40

[19] He L, Wen X, Yan X, Ding L, Cao S, Huang X, Wu R, Wen Y. Effect of cheY deletion on growth and colonization in a Haemophilus parasuis serovar 13 clinical strain EP3. [J]. Gene. 2016; 577(1):96-100

[18] Ding L, Wen X, He L, Yan X, Wen Y, Cao S, Huang X, Wu R, Wen Y. The arcA gene contributes to the serum resistance and virulence of Haemophilus parasuis serovar 13 clinical strain EP3. [J]. Vet Microbiol. 2016; 196:67-71.

[17] Wu R, Wang Q, Liu H, Chai C, He B, Huang X, Wen Y, Wen X, Yan Q, Ma X, Cao S. Phylogenetic analysis reveals that Japanese encephalitis virus genotype III is still prevalent in swine herds in Sichuan province in China. [J]. Arch Virol. 2016; 161(6):1719-22

[16] Dai K, Jin J, Wen Y, Wen X, He L, Cao S, Huang X, Wu R, Zhao Q. Complete Genome Sequence of Highly Virulent Haemophilus parasuis Serotype 11 Strain SC1401. [J]. Genome Announc. 2016; 4(4)

[15] Zhang Y, Zhang X, Liao X, Huang X, Cao S, Wen X, Wen Y, Wu R, Liu W. Construction of a bivalent DNA vaccine co-expressing S genes of transmissible gastroenteritis virus and porcine epidemic diarrhea virus delivered by attenuated Salmonella typhimurium. [J]. Virus Genes. 2016; 52(3):354-64.

[14] Yuan L, Wu R, Liu H, Wen X, Huang X, Wen Y, Ma X, Yan Q, Huang Y, Zhao Q, Cao S. Tissue tropism and molecular characterization of a Japanese encephalitis virus strain isolated from pigs in southwest China. [J]. Virus Res. 2016; 215:55-64.

[13] Yuan L, Wu R, Liu H, Wen X, Huang X, Wen Y, Ma X, Yan Q, Huang Y, Zhao Q, Cao S. The NS3 and NS4A genes as the targets of RNA interference inhibit replication of Japanese encephalitis virus in vitro and in vivo. [J]. Gene. 2016; 594(2):183-189

[12] Wen Y, Yan X, Wen Y, Cao S, He L, Ding L, Zhang L, Zhou P, Huang X, Wu R, Wen X. Immunogenicity of the recombinant HxuCBA proteins encoded by hxuCBA gene cluster of Haemophilus parasuis in mice. [J]. Gene. 2016; 591(2):478-83

[11] Zhang L, Li Y, Wen Y, Lau GW, Huang X, Wu R, Yan Q, Huang Y, Zhao Q, Ma X, Wen X, Cao S. HtrA Is Important for Stress Resistance and Virulence in Haemophilus parasuis. [J]. Infect Immun. 2016; 84(8):2209-2219.

[10] 张小会,张丹,梁恩涛,余敏,黄小波,曹三杰,文心田,文翼平,伍锐. 减毒沙门氏菌投递的TGEVS基因疫苗口服免疫猪的动态规律[J].中国人兽共患病学报,2016,32(01):33-38.

[9] 代军,刘君,黄倩,柳瑶,周鹏,黄毅,谭晓婷,文心田,文翼平,曹三杰,黄小波,伍锐. 副猪嗜血杆菌分型血清制备及其四川地区流行病学[J].中国兽医学报,2016,36(01):24-29.

[8] 滑翔,胡中凯,黄小波,文心田,曹三杰,文翼平,伍锐,邓静,赵松,尹人杰,常晓霞,欧阳达,张仙.检测猪流行性腹泻病毒、猪传染性胃肠炎病毒和猪轮状病毒的cDNA芯片的构建[J].畜牧兽医学报,2015,46(12):2235-2242.

[7] 马锐,文心田,杨国淋,滑翔,赵玉佳,黄小波,曹三杰,文翼平,伍锐. 猪腹泻病毒可视化基因芯片的两种靶基因标记技术的比较[J].中国兽医科学,2016,46(04):409-417.

[6] 马锐,尹人杰,黄小波,文心田,杨国淋,常晓霞,张仙,滑翔,赵玉佳,曹三杰,文翼平,伍锐. 猪病毒性腹泻检测基因芯片的两种样品标记技术比较[J].畜牧兽医学报,2016,47(04):752-761.

[5] 李亚青,黄小波,卿盈,张雨迪,陈杰,文心田,曹三杰,文翼平,伍锐. 猪流行性腹泻病毒ORF3蛋白的生物信息分析及截短原核表达的研究[J].中国兽医科学,2016,46(06):723-730.

[4] 付丹,谭晓婷,曹玉琴,文心田,曹三杰,黄小波,伍锐,文翼平. 副猪嗜血杆菌耐药性研究进展[J].中国预防兽医学报,2016,38(07):591-594.

[3] 马锐,黄小波,杨国淋,滑翔,赵玉佳,文心田,曹三杰,文翼平,伍锐. 猪病毒性腹泻病金标银染可视化芯片技术实验条件优化研究及应用[J].农业生物技术学报,2016,24(08):1233-1242.

[2] 常晓霞,姜来生,曹三杰,文心田,黄小波,邓静,赵松,尹人杰,张仙,杨国淋,马锐,赵玉佳,滑翔. CSFV-PRRSV-JEV联合共检基因芯片的研制与初步应用[J].中国兽医学报,2016,36(09):1469-1475.

[1] 谨瑾,张禄滑,文心田,李英,代科,周鹏,赵玉佳,曹三杰,黄小波,伍锐,赵勤,文翼平. 副猪嗜血杆菌potD基因缺失株的构建及其部分生物学特性[J].畜牧兽医学报,2016,47(11):2274-2279.


2015年发表的论文

[13] He L, Wen X, Yan X, Ding L, Cao S, Huang X, Wu R, Wen Y. Effect of cheY deletion on growth and colonization in a Haemophilus parasuis serovar 13 clinical strain EP3. [J]. Gene. 2016; 577(1):96-100

[12] Zhang L, Li Y, Dai K, Wen X, Wu R, Huang X, Jin J, Xu K, Yan Q, Huang Y, Ma X, Wen Y, Cao S. Establishment of a Successive Markerless Mutation System in Haemophilus parasuis through Natural Transformation. [J]. PLoS One. 2015; 10(5): e0127393.

[11] Zhang L, Cao S, Wu R, Zhu S, Liu H, Yuan L, Shi S, Zhang D, Huang X, Wen X, Wen Y, Yan Q, Huang Y, Ma X. Detection and differentiation of Japanese encephalitis virus genotype I and genotype III by reverse transcription loop-mediated isothermal amplification combined with restriction fragment length polymorphism. [J]. Virus Genes. 2015; 50(2):231-7

[10] 姜宏泽,李英,文心田,黄小波,伍锐,文翼平,张俊,杨瑞晨,曹三杰. 胸膜肺炎放线杆菌抗体ApxⅣ-Dot-PPA-ELISA检测方法的建立[J].中国兽医科学,2015,45(06):633-638.

[9] 张倩,陈广力,文心田,黄小波,伍锐,文翼平,曹三杰. 胸膜肺炎放线杆菌复合减毒突变株WF83ΔapxⅡC/apxⅠAN/apxⅠAC的构建[J].农业生物技术学报,2015,23(07):841-850.

[8] 魏兴良,董敏,张禄滑,丁玲强,赖陆叶,闫雪锋,余敏,文翼平,文心田,黄小波,伍锐,曹三杰. 四川省部分地区副猪嗜血杆菌的分离鉴定及espp2基因序列分析[J].中国兽医学报,2015,35(01):42-49.

[7] 尹杰,杨恒,曹三杰,黄小波,文心田,李洁萍,余正强,周军. 猪传染性胃肠炎病毒S基因B、C位点的克隆与表达及间接ELISA方法的建立[J].中国兽医杂志,2015,51(01):7-10.

[6] 梁恩涛,陈杰,黄小波,文心田,曹三杰,吴学婧,朱书权. 三株递呈猪流行性腹泻病毒S基因的减毒鼠伤寒沙门菌的生物学特性研究[J].畜牧兽医学报,2015,46(02):279-287.

[5] 阳酉萍,黄小波,曹三杰,文心田,梁恩涛,张丹,张小会,段素芬,朱书全,文翼平,伍锐. 四川部分地区猪流行性腹泻的分子流行病学调查[J].中国兽医学报,2015,35(05):704-710.

[4] 欧阳达,姜来生,黄小波,张仙,常晓霞,杨国林,马锐,滑翔,赵玉佳,曹三杰,伍锐,文翼平,文心田. 猪繁殖与呼吸综合征病毒和日本脑炎病毒二联基因芯片的构建与应用[J].中国兽医科学,2015,45(05):509-516.

[3] 张俊,张飞,文心田,冉曦,黄小波,伍锐,文翼平,曹三杰. 四川地区猪传染性胸膜肺炎流行病学调查[J].中国预防兽医学报,2015,37(08):608-610.

[2] 曹玉琴,付丹,杨尧,朱书权,黄小波,文心田,伍锐,文翼平,曹三杰. PEDV-TGEV-RV多重RT-PCR鉴别检测方法的建立及应用[J].中国兽医科学,2015,45(09):881-887.

[1] 张飞,曹三杰,文心田,文翼平,冯彩峰. 猪传染性胸膜肺炎疫苗的研究进展[J].中国兽医学报,2015,35(11):1880-1886.


2014年发表的论文

[8] Zhang L, Wen Y, Li Y, Wei X, Yan X, Wen X, Wu R, Huang X, Huang Y, Yan Q, Liu M, Cao S. Comparative proteomic analysis of the membrane proteins of two Haemophilus parasuis strains to identify proteins that may help in habitat adaptation and pathogenesis. [J]. Proteome Sci. 2014; 12:38.

[7] Wei X, Cao S, Zhang L, Wen X, Wen Y, Wu R, Huang X, Huang Y, Yan Q. Comparative proteome analysis of the extracellular proteins of two Haemophilus parasuis strains Nagasaki and SW114. [J]. Biochem Biophys Res Commun. [J]. 2014;446(4):997-1001

[6] Zhang L, Cao S, Wu R, Zhu S, Liu H, Yuan L, Shi S, Zhang D, Huang X, Wen X, Wen Y, Yan Q, Huang Y, Ma X. Detection and differentiation of Japanese encephalitis virus genotype I and genotype III by reverse transcription loop-mediated isothermal amplification combined with restriction fragment length polymorphism. [J]. Virus Genes. 2015;50(2):231-7

[5] 张洋溢,谢文浩,曹三杰,黄小波,文心田,冉曦,张飞. 三株胸膜肺炎放线杆菌基因缺失株免疫原性的研究[J].中国兽医科学,2014,44(08):862-870.

[4] 梁恩涛,廖晓丹,黄小波,文心田,曹三杰,阳酉萍,段素芬,张丹,张小会. 携带猪流行性腹泻病毒S基因的减毒鼠伤寒沙门菌的构建与鉴定[J].中国兽医科学,2014,44(03):264-270.

[3] 张飞,都启晶,张洋溢,文心田,黄小波,曹三杰. 副猪嗜血杆菌SC-1株荚膜多糖输出蛋白的表达及其免疫原性分析[J].畜牧兽医学报,2014,45(04):621-630.

[2] 邓静,袁明铭,文心田,黄小波,曹三杰,文翼平,伍锐. 猪繁殖与呼吸综合征病毒M基因的截短表达及间接ELISA检测方法的建立[J].中国兽医科学,2014,44(07):734-741.

[1] 邓静,赵春容,曹三杰,文心田,黄小波. 2010-2013年四川地区猪圆环病毒2型的分子流行病学调查[J].中国兽医学报,2014,34(12):1868-1876.